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1

HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis

Kessl, Jacques J., Kutluay, Sebla B., Townsend, Dana, Rebensburg, Stephanie, Slaughter, Alison, Larue, Ross C., Shkriabai, Nikoloz, Bakouche, Nordine, Fuchs, James R., Bieniasz, Paul D., Kvaratskhelia

Journal:

Year:

2016

Language:

english

File:

PDF, 4.46 MB

english, 2016

2

Quinolines from the cyclocondensation of isatoic anhydride with ethyl acetoacetate: preparation of ethyl 4-hydroxy-2-methylquinoline-3-carboxylate and derivatives

Jentsch, Nicholas G, Hume, Jared D, Crull, Emily B, Beauti, Samer M, Pham, Amy H, Pigza, Julie A, Kessl, Jacques J, Donahue, Matthew G

Journal:

Beilstein Journal of Organic Chemistry

Year:

2018

Language:

english

File:

PDF, 433 KB

english, 2018

3

HIV-1 Integrase-DNA Recognition Mechanisms

Kessl, Jacques J., McKee, Christopher J., Eidahl, Jocelyn O., Shkriabai, Nikolozi, Katz, Ari, Kvaratskhelia, Mamuka

Journal:

Year:

2009

Language:

english

File:

PDF, 353 KB

english, 2009

4

The AUG start codon of the Saccharomyces cerevisiae NFS1 gene can be substituted for by UUG without increased initiation of translation at downstream codons

Jürgen H. Nett, Jacques Kessl, Tina Wenz, Bernard L. Trumpower

Journal:

Year:

2001

Language:

english

File:

PDF, 528 KB

english, 2001

5

Synthesis and Evaluation of Aryl Quinolines as HIV-1 Integrase Multimerization Inhibitors

Jentsch, Nicholas G, Hart, Alison P, Hume, Jared D, Sun, Jian, McNeely, Kaitlin A, Lama, Chiyang, Pigza, Julie Alana, Donahue, Matthew G., Kessl, Jacques J

Journal:

ACS Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 590 KB

english, 2018

6

Molecular basis of Toxoplasma gondii atovaquone resistance modeled in Saccharomyces cerevisiae

Jacques J. Kessl, Kevin H. Ha, Anne K. Merritt, Steven R. Meshnick, Bernard L. Trumpower

Journal:

Molecular and Biochemical Parasitology

Year:

2006

Language:

english

File:

PDF, 182 KB

english, 2006

7

A Critical Role of the C-terminal Segment for Allosteric Inhibitor-induced Aberrant Multimerization of HIV-1 Integrase

Shkriabai, Nikoloz, Dharmarajan, Venkatasubramanian, Slaughter, Alison, Kessl, Jacques J., Larue, Ross C., Feng, Lei, Fuchs, James R., Griffin, Patrick R., Kvaratskhelia, Mamuka

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.78 MB

english, 2014

8

Mass spectrometry-based footprinting of protein–protein interactions

Christopher J. McKee, Jacques J. Kessl, Jocelyn O. Norris, Nikolozi Shkriabai, Mamuka Kvaratskhelia

Journal:

Year:

2009

Language:

english

File:

PDF, 185 KB

english, 2009

9

Parameters determining the relative efficacy of hydroxy-naphthoquinone inhibitors of the cytochrome bc1 complex

Jacques J. Kessl, Nikolai V. Moskalev, Gordon W. Gribble, Mohamed Nasr, Steven R. Meshnick, Bernard L. Trumpower

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2007

Language:

english

File:

PDF, 401 KB

english, 2007

10

Indole-based Allosteric Inhibitors of HIV-1 Integrase

Patel, Pratiq A., Kvaratskhelia, Nina, Mansour, Yara, Antwi, Janet, Feng, Lei, Koneru, Pratibha, Kobe, Mathew J., Jena, Nivedita, Shi, Guqin, Mohamed, Mosaad S., Li, Chenglong, Kessl, Jacques J., Fuch

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 1.27 MB

english, 2016

11

The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase

Slaughter, Alison, Jurado, Kellie A, Deng, Nanjie, Feng, Lei, Kessl, Jacques J, Shkriabai, Nikoloz, Larue, Ross C, Fadel, Hind J, Patel, Pratiq A, Jena, Nivedita, Fuchs, James R, Poeschla, Eric, Levy,

Journal:

Year:

2014

Language:

english

File:

PDF, 1.60 MB

english, 2014

12

Allosteric inhibition of HIV-1 integrase activity

Engelman, Alan, Kessl, Jacques J, Kvaratskhelia, Mamuka

Journal:

Current Opinion in Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.04 MB

english, 2013

13

Interaction of the HIV-1 Intasome with Transportin 3 Protein (TNPO3 or TRN-SR2)

Larue, Ross, Gupta, Kushol, Wuensch, Christiane, Shkriabai, Nikolozi, Kessl, Jacques J., Danhart, Eric, Feng, Lei, Taltynov, Oliver, Christ, Frauke, Van Duyne, Gregory D., Debyser, Zeger, Foster, Mark

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 2.49 MB

english, 2012

14

A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase

Sharma, Amit, Slaughter, Alison, Jena, Nivedita, Feng, Lei, Kessl, Jacques J., Fadel, Hind J., Malani, Nirav, Male, Frances, Wu, Li, Poeschla, Eric, Bushman, Frederic D., Fuchs, James R., Kvaratskheli

Journal:

Year:

2014

Language:

english

File:

PDF, 6.42 MB

english, 2014

15

A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain

Patel, Disha, Antwi, Janet, Koneru, Pratibha C, Serrao, Erik, Forli, Stefano, Kessl, Jacques J, Feng, Lei, Deng, Nanjie, Levy, Ronald M., Fuchs, James R., Olson, Arthur J., Engelman, Alan N, Bauman, J

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.32 MB

english, 2016

16

RPL29 codes for a non-essential protein of the 60S ribosomal subunit in Saccharomyces cerevisiae and exhibits synthetic lethality with mutations in genes for proteins required for subunit coupling

Marie Laure DeLabre, Jacques Kessl, Spyridoula Karamanou, Bernard L. Trumpower

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2002

Language:

english

File:

PDF, 200 KB

english, 2002

17

The competitive interplay between allosteric HIV-1 integrase inhibitor BI/D and LEDGF/p75 during the early stage of HIV-1 replication adversely affects inhibitor potency

Feng, Lei, Dharmarajan, Venkatasubramanian, Serrao, Erik, Hoyte, Ashley, Larue, Ross C., Slaughter, Alison, Sharma, Amit, Plumb, Matthew R., Kessl, Jacques J., Fuchs, James R., Bushman, Frederic D., E

Journal:

ACS Chemical Biology

Year:

2016

Language:

english

File:

PDF, 732 KB

english, 2016

18

HIV-1 Integrase-Targeted Short Peptides Derived from a Viral Protein R Sequence

Zhao, Xue, Métifiot, Mathieu, Kiselev, Evgeny, Kessl, Jacques, Maddali, Kasthuraiah, Marchand, Christophe, Kvaratskhelia, Mamuka, Pommier, Yves, Burke, Terrence

Journal:

Year:

2018

Language:

english

File:

PDF, 1.95 MB

english, 2018

19

Modeling the molecular basis of atovaquone resistance in parasites and pathogenic fungi

Jacques J. Kessl, Steven R. Meshnick, Bernard L. Trumpower

Journal:

Trends in Parasitology

Year:

2007

Language:

english

File:

PDF, 1.03 MB

english, 2007

20

Molecular Basis for Atovaquone Resistance in Pneumocystis jirovecii Modeled in the Cytochrome bc 1 Complex of Saccharomyces cerevisiae

Kessl, Jacques J., Hill, Philip, Lange, Benjamin B., Meshnick, Steven R., Meunier, Brigitte, Trumpower, Bernard L.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 1.20 MB

english, 2004

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